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By inhibiting this enzyme, more blood can flow to where it is needed. And, with greater blood flow, the chances that you will achieve and maintain an erection increase, too. This is why medicines like Viagra – and its generic unbranded version, Sildenafil (or Sildenafil Citrate) – are both so popular and so little understood by the general population. Although ED is common, we don’t talk about it as much as we should – and if we come to need the treatments, we don’t really know what it all entails. As such, men usually have a lot of questions about the drug – and that’s perfectly normal.

This helps to ensure tablets are split evenly and minimises wastage by reducing any residue that can fall off a tablet when split incorrectly. You will not be suitable for Viagra and other ED medications if you are taking nicorandil or nitrates, such as GTN spray or isosorbide mononitrate tablets to treat angina. As this is a prescription-only medication, even if you are using an online service, you will need a prescription from a clinician before you can buy the treatment. You should not combine Viagra with other ED medicines including Spedra which can work within 15 minutes.

Using more than one at the same time will not make treatment more effective, and risks overdose and unwanted side effects. Leave a gap between using one type of treatment and another of at least 24 hours. In the rare event of serious side effects seek immediate medical advice (telephone NHS 111 in the UK).

A stronger CYP3A4 inhibitor such as ketoconazole or itraconazole could be expected to have greater effect than that seen with saquinavir. The results from this pilot study are shown in Table 3